Opening Bid - The opening bid is the first non-pass bid made by a player that begins the bidding process. There is only one opening bid, and there is only one "opener" (the player that makes an opening bid). The opener is seat 1. The opening bid is directed to the opener's partner (seat 3), who is asked for a response bid.
Refer to the web page for
Table Position and Opening Bids for a definition of seat number.
Overcall - An overcall is generally the first bid made by the oppostion immediately after the opening bid. The person that makes the overcall is the "overcaller", and is generally seat 2. The overcall is directed to the overcaller's partner (seat 4).
Sometimes the overcaller might be in seat 4. In this case, seat 2 has passed, and seat 3 might or might not have passed. Nonetheless, seat 4 is the first opponent to bid after the opening bid (seat 1). This overcall is still directed to the overcaller's partner, this time in seat 2.